Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057720 | 0.96 | ALDH1A1 (0.39) | SMN1; SMN2LMNANR1I2HTTF10 | |
| SCHEMBL11054620 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANR1I2GAAHTT | |
| Hydrochloric Acid SCHEMBL11558027 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATAAR1ALDH1A1CYP3A4 | |
| SCHEMBL11056570 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNANR1I2ALDH1A1ACHE | |
| SCHEMBL11061902 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTTOPRM1ALDH1A1 | |
| SCHEMBL11053014 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAHTTF10OPRM1 | |
| SCHEMBL11056622 | 0.85 | OPRM1 (0.38) | SMN1; SMN2LMNAOPRM1CYP3A4ACHE | |
| SCHEMBL11056986 | 0.85 | ALDH1A1 (0.38) | SMN1; SMN2LMNAOPRM1ALDH1A1TP53 | |
| SCHEMBL11053216 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNANR1I2HTTTDP1 | |
| SCHEMBL11060088 | 0.83 | TP53 (0.42) | SMN1; SMN2NR1I2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |