Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11558027 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAL3MBTL1HPGDP2RX7 | |
| SCHEMBL11053515 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAL3MBTL1HPGDP2RX7 | |
| SCHEMBL11056622 | 0.88 | OPRM1 (0.38) | SMN1; SMN2LMNAL3MBTL1HPGDP2RX7 | |
| SCHEMBL11057720 | 0.88 | ALDH1A1 (0.39) | SMN1; SMN2LMNAL3MBTL1HPGDP2RX7 | |
| SCHEMBL11055968 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNACYP3A4F10HTT | |
| SCHEMBL11056521 | 0.84 | HPGD (0.40) | SMN1; SMN2L3MBTL1HPGDCYP2C9HTT | |
| Hydrochloric Acid SCHEMBL11557076 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1P2RX7KMT2A | |
| Hydrochloric Acid SCHEMBL11562331 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHPGDP2RX7HTT | |
| SCHEMBL11057304 | 0.81 | L3MBTL1 (0.38) | LMNAL3MBTL1HPGDCYP3A4F10 | |
| Hydrochloric Acid SCHEMBL11581693 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2L3MBTL1HPGDCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |