Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL29244059 | 0.82 | ALDH1A1 (0.56) | CA5ACA5BANPEPERAP2ALDH1A1 | |
| Nitric Acid SCHEMBL28858089 | 0.82 | ALDH1A1 (0.56) | CA5ACA5BANPEPERAP2ALDH1A1 | |
| Nitric Acid SCHEMBL7914060 | 0.81 | — | — | |
| Nitric Acid SCHEMBL11327425 | 0.79 | CA5A (0.67) | CA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL23270365 | 0.79 | — | — | |
| Nitric Acid SCHEMBL29242395 | 0.79 | CA5A (0.47) | CA5ACA5B | |
| Nitric Acid SCHEMBL29270163 | 0.79 | — | — | |
| Nitric Acid SCHEMBL10579131 | 0.77 | — | — | |
| Ethylenediamine SCHEMBL721753 | 0.76 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1 | |
| Ethylenediamine SCHEMBL6232364 | 0.76 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481048-A | AMMONIUM NITRATE AND DIETHYLENETRIAMINE TRINITRATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1984-11-06 | — | — | US | disclosed |