Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL6232364 | 1.00 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1TSHR | |
| Ethylenediamine SCHEMBL28858090 | 1.00 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1TSHR | |
| Ethylenediamine SCHEMBL723589 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL2733332 | 1.00 | CA5A (0.61) | CA5ACA5BALDH1A1TDP1TSHR | |
| Ethylenediamine SCHEMBL4419318 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL11236240 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL6157507 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL28246966 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL4419325 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL8214214 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | ALTI LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-12517047-B2 | Transport and detection of explosive samples | ALTI LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-20250237601-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES | ALTI LLC | 2025-07-24 | — | — | US | claimed |
| US-20240391848-A1 | EMULSION EXPLOSIVE COMPOSITION FOR BOOSTER OF BULK EXPLOSIVE | HANWHA CORPORATION (KR) | 2024-11-28 | — | — | US | claimed |
| CN-116411326-B | Aluminum alloy composite material and preparation method thereof | 比亚迪股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-115724808-B | Olefin epoxidation method | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-116411326-A | Aluminum alloy composite material and preparation method thereof | 比亚迪股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| WO-2023106587-A1 | EMULSION EXPLOSIVE COMPOSITION FOR PRE-EXPLOSIVES OF BULK EXPLOSIVES | 주식회사 한화 | 2023-06-15 | — | — | WO | claimed |
| US-20210253492-A1 | SYSTEMS FOR PRODUCING DEMN EUTECTIC | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2021-08-19 | — | — | US | claimed |
| US-10836687-B2 | Systems for producing DEMN eutectic, and related methods of forming an energetic composition | Northrop Grumman Innovation Systems, Inc. (US) | 2020-11-17 | — | — | US | claimed |
| US-4371408-A | DETONATION CATALYSTS AND SENSITIZERS | ATLAS POWDER COMPANY (US) | 1983-02-01 | — | — | US | claimed |
| US-4353758-A | Direct process for explosives | AKST IRVING B | 1982-10-12 | — | — | US | claimed |
| US-4248644-A | WATER FREE, GREASY, CONTAINING AMMONIUM NITRATE AND AN EMULSIFIER | AECI LIMITED (ZA) | 1981-02-03 | — | — | US | claimed |
| US-4141766-A | OXIDIZER, SENSITIZING FUEL OF ALIPHATIC MONONITRATE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | claimed |
| US-4115165-A | Hydrophobic aluminum sensitizing agents for explosives | ATLAS POWDER COMPANY (US) | 1978-09-19 | — | — | US | claimed |
| US-4110136-A | 1,3,5-TRINITRO-1,3,5-TRIAZACYCLOHEXANE AND/OR 1,3,5,7-TETRANITRO-1,3,5,7-TETRAZACYCLOOCTANE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1978-08-29 | — | — | US | claimed |
| US-4104092-A | INORGANIC OXIDIZERS, WATER, BULKING AGENTS, CARBONACEOUS FUEL | ATLAS POWDER COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4097316-A | INORGANIC NITRATE, THICKENERS, GELLING AGENTS, STORAGE STABILITY | ATLAS POWDER COMPANY (US) | 1978-06-27 | — | — | US | claimed |
| US-4025591-A | ACRYLIC ESTER CURING MONOMER, ORGANIC PEROXIDE CATALYST | JET RESEARCH CENTER, INC. (US) | 1977-05-24 | — | — | US | claimed |
| US-3957550-A | EXPLOSIVES, LIQUID FUELS, OXIDIZERS | THIOKOL CORPORATION (US) | 1976-05-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110607-A1 | TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES | TES, TNPO1, SLC2A1 | CA5A 1216/4885CA5B 993/4885ALDH1A1 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.