Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109138 | 0.91 | HDAC1 (0.52) | HDAC1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL400733 | 0.90 | MEN1 (0.48) | MEN1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL404569 | 0.86 | MEN1 (0.47) | HDAC1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL401321 | 0.85 | HDAC1 (0.50) | HDAC1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL402708 | 0.82 | HDAC1 (0.47) | HDAC1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL406023 | 0.81 | HDAC1 (0.48) | HDAC1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL405583 | 0.81 | — | — | |
| SCHEMBL1912129 | 0.81 | ALDH1A1 (0.51) | HDAC1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL402556 | 0.80 | NAMPT (0.40) | — | |
| SCHEMBL13818643 | 0.80 | HDAC1 (0.38) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153843-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | HDAC1 824/4885MEN1 2414/4885ALDH1A1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.