Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069275 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBMAPK1CSGALNACT1 | |
| SCHEMBL11464328 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBHPGDADAMTS4 | |
| SCHEMBL11217171 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBMAPK1CSGALNACT1 | |
| SCHEMBL4551445 | 0.84 | ALDH1A1 (0.51) | ALDH1A1POLBMAPK1HPGDAKR1C3 | |
| SCHEMBL11056124 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBMMP13GAA | |
| SCHEMBL11202529 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL11202526 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL2794117 | 0.78 | POLB (0.40) | ALDH1A1POLBMAPK1HPGDAKR1C3 | |
| SCHEMBL11194644 | 0.77 | RAB9A (0.48) | ALDH1A1POLBCSGALNACT1HPGDADAMTS4 | |
| SCHEMBL11194641 | 0.77 | RAB9A (0.48) | ALDH1A1POLBCSGALNACT1HPGDADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466927-A | FROM N-(TRIFLUOROMETHYL)ANTHRANILOYL FLUORIDE WITH HYDROGEN FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4411912-A | Insecticidal isovaleric acid esters | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |