Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144630 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2HTTALDH1A1TSHR | |
| SCHEMBL28899369 | 0.82 | GABRA1 (0.43) | GABRA1GABRB2HTTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL668040 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2HTTALDH1A1TSHR | |
| Bromide SCHEMBL4908296 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2HTTALDH1A1TSHR | |
| Water SCHEMBL2836979 | 0.81 | GABRA1 (0.38) | GABRA1GABRB2HTTALDH1A1TSHR | |
| Iodide SCHEMBL19307326 | 0.78 | GABRA1 (0.36) | GABRA1GABRB2HTTALDH1A1TSHR | |
| SCHEMBL24440219 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2HTTALDH1A1MAPT | |
| SCHEMBL11778390 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2HTTALDH1A1TSHR | |
| SCHEMBL278267 | 0.77 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1TSHRICAM1 | |
| SCHEMBL790381 | 0.75 | GABRA1 (0.39) | GABRA1GABRB2HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031424-B1 | POLYESTERS OF N,N-DI-ALKANOL-AMINES WITH DI-(HYDROXY-ALKYL-BENZYL)MALONIC ACIDS, AND COMPOSITIONS CONTAINING SAME AS STABILIZERS | Montedison S.p.A. (IT) | 1984-07-25 | — | — | EP | disclosed |
| US-4361695-A | Polyesters of N,N-di-alkanol-amines with di-(hydroxy-alkyl-benzyl) malonic acids and use thereof as stabilizers for polymers | MONTEDISON S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |