SCHEMBL790381

SCHEMBL790381

C=CCc1ccccc1C(S)(CC=C)CC=C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HTT P42858 1/20 0.32
AKR1B1 P15121 1/20 0.31
ADRA2C P18825 3/20 0.31
ADRA2B P18089 2/20 0.31
HTR1A P08908 2/20 0.31
ADRA2A P08913 1/20 0.31
NISCH Q9Y2I1 1/20 0.31
MAPT P10636 1/20 0.30
LMNA P02545 1/20 0.30
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30
SLC6A2 P23975 1/20 0.30
BDKRB2 P30411 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659100 0.81 GABRA1 (0.39) GABRA1GABRB2ALDH1A1TSHRKDM4E
SCHEMBL792521 0.78 GABRA1 (0.39) GABRA1GABRB2ALDH1A1TSHRKDM4E
SCHEMBL28899369 0.78 GABRA1 (0.43) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL14472081 0.78 GABRA1 (0.39) GABRA1GABRB2ALDH1A1TSHRKDM4E
SCHEMBL144630 0.78 GABRA1 (0.39) GABRA1GABRB2ALDH1A1TSHRKDM4E
Water SCHEMBL2836979 0.76 GABRA1 (0.38) GABRA1GABRB2ALDH1A1TSHRKDM4E
Hydrochloric Acid SCHEMBL668040 0.76 GABRA1 (0.38) GABRA1GABRB2ALDH1A1TSHRKDM4E
Bromide SCHEMBL4908296 0.76 GABRA1 (0.38) GABRA1GABRB2ALDH1A1TSHRKDM4E
SCHEMBL11056233 0.75 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TSHRHTT
SCHEMBL8522980 0.75 GABRA1 (0.42) GABRA1GABRB2ALDH1A1KDM4EAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11884839-B2 Acetal-protected silanol group-containing polysiloxane composition NISSAN CHEMICAL CORPORATION (JP) 2024-01-30 US disclosed
US-10845703-B2 Film-forming composition containing silicone having crosslinking reactivity NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-11-24 US disclosed
US-10838303-B2 Resist underlayer film forming composition for lithography containing hydrolyzable silane having carbonate skeleton NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-11-17 US disclosed
US-10613440-B2 Silicon-containing EUV resist underlayer film-forming composition containing onium sulfonate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-04-07 US disclosed
US-10372040-B2 Resist underlayer film forming composition for lithography containing hydrolyzable silane having halogen-containing carboxylic acid amide group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-08-06 US disclosed
US-10372039-B2 Resist underlayer film forming composition containing silicon having ester group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-08-06 US disclosed
US-20190185707-A1 ACETAL-PROTECTED SILANOL GROUP-CONTAINING POLYSILOXANE COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2019-06-20 US disclosed
US-10139729-B2 Coating composition for pattern reversal on soc pattern NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-11-27 US disclosed
US-20180335698-A1 FILM-FORMING COMPOSITION CONTAINING SILICONE HAVING CROSSLINKING REACTIVITY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-11-22 US disclosed
US-20180239250-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING HYDROLYZABLE SILANE HAVING CARBONATE SKELETON NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-23 US disclosed
US-9023588-B2 Resist underlayer film forming composition containing silicon having nitrogen-containing ring NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-05-05 US disclosed
US-20150118396-A1 UNDERLAYER FILM-FORMING COMPOSITION FOR SELF-ASSEMBLED FILMS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-30 US disclosed
EP-2832807-A1 UNDERLAYER FILM FORMING COMPOSITION FOR SELF-ASSEMBLED FILMS Nissan Chemical Industries, Ltd. (JP) 2015-02-04 EP disclosed
US-20140377957-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION FOR SOLVENT DEVELOPMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-25 US disclosed
US-20140170855-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING SULFONE STRUCTURE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-19 US disclosed
EP-2735904-A1 THIN FILM FORMATION COMPOSITION FOR LITHOGRAPHY WHICH CONTAINS TITANIUM AND SILICON Nissan Chemical Industries, Ltd. (JP) 2014-05-28 EP disclosed
US-20140120730-A1 THIN FILM FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING TITANIUM AND SILICON NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-01 US disclosed
EP-2538276-A1 COMPOSITION FOR FORMATION OF RESIST UNDERLAYER FILM CONTAINING SILICON HAVING NITROGEN-CONTAINING RING Nissan Chemical Industries, Ltd. (JP) 2012-12-26 EP disclosed
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-12-13 US disclosed
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120315765-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING NITROGEN-CONTAINING RING SRSF1, SRSF7, SRRM2 GABRA1 4445/4885GABRB2 3844/4885ALDH1A1 2272/4885
US-20120070994-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFIDE BOND SMC3, SRSF3, SRSF9 GABRA1 3568/4885GABRB2 3428/4885ALDH1A1 3278/4885
US-10845703-B2 Film-forming composition containing silicone having crosslinking reactivity SETDB1, KDM2B, SRSF9 GABRA1 4090/4885GABRB2 3316/4885ALDH1A1 1744/4885
US-20180335698-A1 FILM-FORMING COMPOSITION CONTAINING SILICONE HAVING CROSSLINKING REACTIVITY SETDB1, KDM2B, CD79B GABRA1 4184/4885GABRB2 3272/4885ALDH1A1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.