Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060435 | 0.89 | CRBN (0.56) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| Water SCHEMBL28110279 | 0.87 | CRBN (0.55) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| SCHEMBL22720116 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| SCHEMBL13161898 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| SCHEMBL29229446 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL2154833 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL2771765 | 0.83 | CRBN (0.51) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| SCHEMBL31465178 | 0.83 | NPC1 (0.71) | ALDH1A1KDM4EHTR4CHEK1PARP1 | |
| SCHEMBL28510668 | 0.83 | CRBN (0.51) | ALDH1A1KDM4ECRBNLMNANPC1 | |
| SCHEMBL2771766 | 0.83 | CRBN (0.51) | ALDH1A1KDM4ECRBNLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486442-A | ANTIANAPHYLACTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1984-12-04 | — | — | US | disclosed |