Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060199 | 0.99 | NAAA (0.39) | NAAAHPGDMAPK1NPSR1L3MBTL1 | |
| SCHEMBL11058223 | 0.96 | ALOX5 (0.39) | ALOX5HPGDHDAC6ALDH1A1HTT | |
| SCHEMBL11057304 | 0.92 | L3MBTL1 (0.38) | ALOX5HPGDMAPK1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11556716 | 0.90 | NAAA (0.40) | NAAAALOX5HPGDMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL11561808 | 0.89 | NAAA (0.42) | NAAAHPGDMAPK1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11561818 | 0.89 | NAAA (0.42) | NAAAHPGDMAPK1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11558614 | 0.89 | NAAA (0.42) | NAAAHPGDMAPK1NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11565507 | 0.89 | NAAA (0.42) | NAAAHPGDMAPK1NPSR1L3MBTL1 | |
| SCHEMBL11057738 | 0.87 | TDP1 (0.39) | NAAAALOX5HPGDMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL11562345 | 0.87 | ALOX5 (0.42) | NAAAALOX5HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |