Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 5/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12389676 | 0.82 | MAPT (0.62) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL456985 | 0.80 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL4957765 | 0.79 | MAPT (0.72) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL18019596 | 0.79 | NPC1 (0.69) | L3MBTL1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL455344 | 0.79 | IDO1 (0.78) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL15798566 | 0.78 | HDAC2 (0.55) | ALDH1A1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL1105708 | 0.77 | HDAC2 (0.59) | KMT2AMAPTMEN1SMN1; SMN2HDAC2 | |
| SCHEMBL10155589 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL10153970 | 0.76 | CACNA1B (0.67) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL11774528 | 0.76 | NPC1 (0.59) | KMT2AKDM4EMAPTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153100-B2 | Methods and compositions for F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-8147800-B2 | Methods and compositions for F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20110280801-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, TFRC, F13A1 | ALDH1A1 4778/4885L3MBTL1 2077/4885KMT2A 2351/4885 |
| US-20110280801-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | TFRC, F13A1, S100A8 | ALDH1A1 4670/4885L3MBTL1 1832/4885KMT2A 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.