Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058573 | 0.84 | CHRM4 (0.42) | MAPTHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL11056958 | 0.73 | RAB9A (0.50) | POLBMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL11054242 | 0.73 | MAPT (0.60) | MAPTPOLBSHMT2GAA | |
| SCHEMBL15084379 | 0.68 | MEN1 (0.55) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL15081974 | 0.68 | MEN1 (0.52) | MAPTPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL15522838 | 0.67 | GAA (0.39) | MAPTMEN1KMT2AGAA | |
| SCHEMBL29643512 | 0.67 | ALDH1A1 (0.47) | MAPTHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL23057171 | 0.65 | GAA (0.45) | MAPTPOLBSHMT2HTR2CHTR2B | |
| SCHEMBL11055326 | 0.65 | MEN1 (0.66) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6540431 | 0.65 | TACR1 (0.46) | MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | claimed |
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |