Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055326 | 0.85 | MEN1 (0.66) | RAB9AHTR1AKMT2AMEN1KDM4E | |
| SCHEMBL11056954 | 0.78 | KMT2A (0.58) | KMT2AMEN1KDM4EALDH1A1RECQL | |
| SCHEMBL13879410 | 0.75 | KDM4E (0.57) | RAB9AHTR1AKMT2AMEN1KDM4E | |
| SCHEMBL11061243 | 0.74 | KMT2A (0.60) | HTR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11056757 | 0.73 | MAPT (0.46) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL11061195 | 0.73 | POLB (0.52) | HTR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13879455 | 0.71 | KDM4E (0.56) | RAB9AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11825396 | 0.67 | AADAT (0.49) | KMT2AMEN1KDM4EALDH1A1RECQL | |
| SCHEMBL11821643 | 0.67 | AADAT (0.46) | RAB9AKDM4EALDH1A1RECQLPOLB | |
| SCHEMBL5746794 | 0.66 | HTR1A (0.60) | HTR1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | claimed |
| US-4446323-A | Tetra- and hexa-hydropyrrolo(1,2-a)quinoxaline and azaquinoxaline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |