SCHEMBL1105676

SCHEMBL1105676

Cc1ccc2c(c1)cc1ccccn12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
PDE10A Q9Y233 2/20 0.41
CYP1A2 P05177 3/20 0.38
MAPT P10636 4/20 0.37
RXFP1 Q9HBX9 1/20 0.37
NSD2 O96028 1/20 0.37
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
GAA P10253 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30307422 0.78 ALDH1A1 (0.42) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL64923 0.78 ALDH1A1 (0.42) TDP1KDM4EALDH1A1RAB9ANPC1
Perchlorate SCHEMBL4790551 0.69 ALDH1A1 (0.36) KDM4EALDH1A1RAB9ANPC1CYP1A2
SCHEMBL19229363 0.69 KDM4E (0.38) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL8581523 0.68 ALDH1A1 (0.42) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL24553486 0.68 ALDH1A1 (0.60) KDM4EALDH1A1RAB9ANPC1PDE10A
SCHEMBL26168101 0.68 MAPT (0.34) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL22427835 0.67 MAPT (0.33) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL31612371 0.67 ALDH1A1 (0.62) TDP1KDM4EALDH1A1RAB9ANPC1
SCHEMBL5797639 0.67 ALDH1A1 (0.44) CYP2A6TDP1KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4008790-B1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM INC (US) 2024-07-17 EP disclosed
EP-4008790-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS Enzo Biochem, Inc. (US) 2022-06-08 EP disclosed
EP-3277832-B1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM INC (US) 2021-10-06 EP disclosed
US-20210079225-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM, INC. (US) 2021-03-18 US disclosed
US-20180215920-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCERS ENZO BIOCHEM, INC. (US) 2018-08-02 US disclosed
US-9957393-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-05-01 US disclosed
US-9957393-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-05-01 US disclosed
US-9951227-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-04-24 US disclosed
US-9951227-B2 Monoazo dyes with cyclic amine as fluorescence quenchers ENZO BIOCHEM, INC. (US) 2018-04-24 US disclosed
US-9932479-B2 Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications ENZO BIOCHEM, INC. (US) 2018-04-03 US disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest ENZO LIFE SCIENCES, INC. 2010-03-18 US disclosed
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest ENZO LIFE SCIENCES, INC. 2010-03-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20100041020-A1 Methods for detecting the presence, location or quantity of targets using novel dyes ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-02-18 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits SSBP1, IMMT, DNAJA3 CYP2A6 4843/4885TDP1 972/4885KDM4E 4671/4885
US-20100068752-A1 Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest SSBP1, YARS1, ANXA5 CYP2A6 4849/4885TDP1 673/4885KDM4E 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.