SCHEMBL64923

SCHEMBL64923

c1ccc2c(c1)cc1ccccn12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
KDM4E B2RXH2 7/20 0.42
GLA P06280 4/20 0.42
GAA P10253 4/20 0.42
HPGD P15428 4/20 0.42
HSD17B10 Q99714 3/20 0.42
MAPT P10636 5/20 0.38
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
CDK4 P11802 3/20 0.35
CCND1 P24385 3/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
DAO P14920 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30307422 1.00 ALDH1A1 (0.42) ALDH1A1KDM4EGLAGAAHPGD
Perchlorate SCHEMBL4790551 0.89 ALDH1A1 (0.36) ALDH1A1KDM4EGLAGAAHPGD
Fumaric Acid SCHEMBL11114413 0.84 L3MBTL1 (0.47) ALDH1A1KDM4EHPGDMAPTNPC1
Maleic Acid SCHEMBL11114411 0.84 L3MBTL1 (0.47) ALDH1A1KDM4EHPGDMAPTNPC1
SCHEMBL1105676 0.78 CYP2A6 (0.42) ALDH1A1KDM4EGAAMAPTNPC1
SCHEMBL29681513 0.78 DAO (0.36) ALDH1A1KDM4EGLAGAAHPGD
SCHEMBL1958088 0.77 ALDH1A1 (0.47) ALDH1A1KDM4EGLAGAAHPGD
SCHEMBL29769929 0.77 ALDH1A1 (0.47) ALDH1A1KDM4EGLAGAAHPGD
SCHEMBL6851190 0.75 BAZ2B (0.45) ALDH1A1KDM4EHSD17B10MAPTL3MBTL1
SCHEMBL8581523 0.75 ALDH1A1 (0.42) ALDH1A1KDM4EGLAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129065-B1 TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS AKAMARA THERAPEUTICS INC (US) 2026-05-13 EP disclosed
EP-3672582-B1 COMPOSITIONS AND METHODS FOR TREATING CANCER CEDARS SINAI MEDICAL CENTER (US) 2026-04-15 EP disclosed
EP-4709483-A1 NEW 5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE DERIVATIVES AND 6,7,8,9-TETRAHYDRO-5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE USEFUL IN THE TREATMENT OF CANCER Institut Regional du Cancer de Montpellier (FR) 2026-03-18 EP disclosed
US-12569486-B2 Calmodulin inhibitors, CHK2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2026-03-10 US disclosed
EP-4229055-B1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS NOVARTIS AG (CH) 2026-03-04 EP disclosed
US-12560609-B2 Biomarkers predictive of cancer cell response to ML329 or a derivative thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-02-24 US disclosed
US-20260015316-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER CEDARS-SINAI MEDICAL CENTER (US) 2026-01-15 US disclosed
US-20250388597-A1 BIFUNCTIONAL PHOTOCROSSLINKING PROBES FOR COVALENT CAPTURE OF PROTEIN-NUCLEIC ACID COMPLEXES IN CELLS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-12-25 US disclosed
US-12503526-B2 Nickel catalysts with single alkali ions for homopolymerization and copolymerization UNIVERSITY OF HOUSTON SYSTEM (US) 2025-12-23 US disclosed
US-20250361333-A1 METHODS FOR PREPARING COPOLYMERS AND FOR THE OXIDATIVE DEGRADATION THEREOF UNIVERSITY OF HOUSTON SYSTEM (US) 2025-11-27 US disclosed
US-4968699-A CENTRAL NERVOUS SYSTEM; ANTIISCHEMIC AND ANTIHYPOXIC AGENTS; ACTIVE AGAINST CEREBRAL OXYGEN DEFICIENCY BEECHAM-WUELFING GMBH & CO. (DE) 1990-11-06 US disclosed
US-4853391-A Pyrido[1,2-a]indoles and their use as cardiovascular LABORATOIRES SOBIO SA, 13-15-25 BOULEVARD DE 1'AMIRAL BRUIX 75782 PARIS, CEDEX 16, FRANCE 1989-08-01 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0252643-A1 Pyrido[1,2-a]indole derivatives, process for their preparation and pharmaceutical compounds containing them BEECHAM - WUELFING GmbH & Co. KG (DE) 1988-01-13 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-3983288-A Fibers and fabrics containing optical brightening agents EASTMAN KODAK COMPANY (US) 1976-09-28 US disclosed
US-3983288-A Fibers and fabrics containing optical brightening agents EASTMAN KODAK COMPANY (US) 1976-09-28 US disclosed
US-3860886-A DYE LASER AND METHOD EASTMAN KODAK CO 1975-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569486-B2 Calmodulin inhibitors, CHK2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies RPS6KA1, RPS6KA2, RPS6KA3 ALDH1A1 4383/4885KDM4E 2379/4885GLA 3191/4885
US-12560609-B2 Biomarkers predictive of cancer cell response to ML329 or a derivative thereof KEAP1, NFE2L2, NQO1 ALDH1A1 299/4885KDM4E 680/4885GLA 3533/4885
US-20250388597-A1 BIFUNCTIONAL PHOTOCROSSLINKING PROBES FOR COVALENT CAPTURE OF PROTEIN-NUCLEIC ACID COMPLEXES IN CELLS PCNA, DDB1, DCLRE1A ALDH1A1 3514/4885KDM4E 877/4885GLA 3472/4885
US-20260015316-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER GLI1, RCC2, BRCA1 ALDH1A1 1253/4885KDM4E 1875/4885GLA 3618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.