Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422483 | 0.76 | SMN1; SMN2 (0.34) | KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21393237 | 0.75 | F2 (0.37) | TP53HDAC6 | |
| SCHEMBL293304 | 0.73 | POLB (0.37) | KDM4ETP53HSD17B10LMNAHDAC1 | |
| SCHEMBL11764937 | 0.73 | L3MBTL1 (0.33) | LMNASMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL23081582 | 0.71 | RAB9A (0.34) | KDM4ETP53HSD17B10HDAC1HDAC6 | |
| SCHEMBL11418813 | 0.71 | HDAC1 (0.33) | HDAC1HDAC6 | |
| SCHEMBL11690867 | 0.70 | HDAC1 (0.32) | HDAC1HDAC6 | |
| SCHEMBL11764620 | 0.70 | HDAC6 (0.34) | TP53LMNASMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL11421273 | 0.70 | — | — | |
| SCHEMBL19685887 | 0.69 | KDM4E (0.33) | KDM4ELMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046731-B1 | PROCESS FOR THE PRODUCTION OF DI- AND POLYALLYL ETHERS | CIBA-GEIGY AG (CH) | 1984-10-03 | — | — | EP | disclosed |
| US-4433179-A | Process for the preparation of di- and poly-allyl ethers | CIBA-GEIGY CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
| US-4013698-A | POLYSILOXANES CONTAINING HYDROXYL GROUPS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3981898-A | FLEXIBILITY MODIFIERS, HYDROPHOBIC | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |