Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055671 | 0.94 | FAAH (0.63) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL5720369 | 0.93 | FAAH (0.62) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL11059455 | 0.92 | FAAH (0.61) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL5720077 | 0.92 | FAAH (0.61) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL10810536 | 0.92 | FAAH (0.61) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL11052412 | 0.92 | FAAH (0.61) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL10812434 | 0.86 | FAAH (0.43) | FAAHMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10814092 | 0.84 | FAAH (0.52) | FAAHMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5720580 | 0.84 | FAAH (0.52) | FAAHMEN1KMT2ANPSR1POLB | |
| SCHEMBL11059270 | 0.83 | FAAH (0.53) | FAAHMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0104342-A1 | Triphenylimidazolyloxyalcanoic acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | A. Nattermann & Cie. GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |