Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810536 | 0.92 | FAAH (0.61) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL5720077 | 0.92 | FAAH (0.61) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL11052412 | 0.92 | FAAH (0.61) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL11059455 | 0.92 | FAAH (0.61) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL5720369 | 0.91 | FAAH (0.62) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL11113206 | 0.88 | ALDH1A1 (0.53) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL10815797 | 0.88 | ALDH1A1 (0.53) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL11058331 | 0.87 | FAAH (0.56) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL10814504 | 0.87 | FAAH (0.56) | FAAHLMNAL3MBTL1ALDH1A1NPY1R | |
| SCHEMBL10818300 | 0.87 | FAAH (0.56) | FAAHLMNAL3MBTL1ALDH1A1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104342-B1 | TRIPHENYLIMIDAZOLYLOXYALCANOIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |