Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810536 | 1.00 | FAAH (0.61) | FAAHMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL11059455 | 1.00 | FAAH (0.61) | FAAHMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL11052412 | 1.00 | FAAH (0.61) | FAAHMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL5720369 | 0.99 | FAAH (0.62) | FAAHMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL11055671 | 0.96 | FAAH (0.63) | FAAHMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL11056914 | 0.92 | FAAH (0.59) | FAAHMEN1KMT2APOLBNPSR1 | |
| SCHEMBL10814092 | 0.92 | FAAH (0.52) | FAAHMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10814504 | 0.89 | FAAH (0.56) | FAAHMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11058331 | 0.89 | FAAH (0.56) | FAAHMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10818300 | 0.89 | FAAH (0.56) | FAAHMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841910-A4 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-0841910-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997004765-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |
| US-4460598-A | Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases | A. NATTERMANN & CIE GMBH (DE) | 1984-07-17 | — | — | US | disclosed |