SCHEMBL1105764

SCHEMBL1105764

CC(C)(C)OC(=O)NCC(CO)(CNC(=O)OC(C)(C)C)CNC(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 4/20 0.39
CA2 P00918 4/20 0.39
CA12 O43570 4/20 0.39
CA9 Q16790 2/20 0.39
EPHX1 P07099 1/20 0.39
CA7 P43166 2/20 0.38
CTSS P25774 3/20 0.37
CTSK P43235 3/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
CA14 Q9ULX7 2/20 0.36
APLNR P35414 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18290156 0.84 TDP1 (0.58) TDP1MEN1KMT2AGAAMAOA
SCHEMBL1105697 0.83 TDP1 (0.47) TDP1MEN1KMT2AGAAMAOA
SCHEMBL571043 0.83 TDP1 (0.52) TDP1MEN1KMT2AGAAMAOA
SCHEMBL28760650 0.82 TDP1 (0.50) TDP1MEN1KMT2AGAAMAOA
SCHEMBL22449920 0.82 TDP1 (0.50) TDP1MEN1KMT2AGAAMAOA
SCHEMBL842921 0.80 TDP1 (0.52) TDP1MEN1KMT2AGAAMAOA
SCHEMBL21065336 0.80 TDP1 (0.52) TDP1MEN1KMT2AGAAMAOA
SCHEMBL255203 0.80 TDP1 (0.52) TDP1MEN1KMT2AGAAMAOA
SCHEMBL13449471 0.80 TDP1 (0.49) TDP1MEN1KMT2AGAAMAOA
Alcohol SCHEMBL6893768 0.80 TDP1 (0.49) TDP1MEN1KMT2AGAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827586-B2 Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-11-28 US disclosed
US-9522962-B2 Peptides, conjugates and method for increasing immunogenicity of a vaccine ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2016-12-20 US disclosed
EP-2547364-B1 Peptides, conjugates and method for increasing immunogenicity of a vaccine ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2016-12-14 EP disclosed
US-8445611-B2 Antimicrobial polymers UNIVERSITY OF MASSACHUSETTS (US) 2013-05-21 US disclosed
US-8445611-B2 Antimicrobial polymers UNIVERSITY OF MASSACHUSETTS (US) 2013-05-21 US disclosed
US-20130071428-A1 PEPTIDES, CONJUGATES AND METHOD FOR INCREASING IMMUNOGENICITY OF A VACCINE STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2013-03-21 US disclosed
US-20120195849-A1 ANTIMICROBIAL POLYMERS MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT 2012-08-02 US disclosed
US-8153739-B2 Antimicrobial polymers UNIVERSITY OF MASSACHUSETTS (US) 2012-04-10 US disclosed
US-20100317870-A1 ANTIMICROBIAL POLYMERS MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317870-A1 ANTIMICROBIAL POLYMERS CGAS, NOD2, NLRP1 TDP1 3005/4885MEN1 104/4885KMT2A 3663/4885
US-20120195849-A1 ANTIMICROBIAL POLYMERS CGAS, NOD2, NLRP1 TDP1 3005/4885MEN1 104/4885KMT2A 3663/4885
US-11827586-B2 Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof SLC6A15, SLC6A19, ALAD TDP1 4422/4885MEN1 2569/4885KMT2A 3098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.