SCHEMBL11057735

SCHEMBL11057735

C=C1CCC(=C)c2c1cccc2-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
HNF4A P41235 1/20 0.37
PRCP P42785 1/20 0.37
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HTR1A P08908 2/20 0.36
HTR7 P34969 2/20 0.36
DRD2 P14416 1/20 0.36
CES1 P23141 1/20 0.35
PTGS2 P35354 1/20 0.34
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6006940 0.74 MEN1 (0.39) CYP2A6PARP10PARP11ALDH1A1MAPK1
Ethylene SCHEMBL27763808 0.72 ALDH1A1 (0.46) CYP2A6HNF4AALDH1A1HSD17B10HPGD
SCHEMBL192418 0.71 ALDH1A1 (0.50) CYP2A6HNF4AALDH1A1HSD17B10HPGD
SCHEMBL29370260 0.70 CES1 (0.54) CYP2A6PARP10PARP11ALDH1A1HPGD
SCHEMBL66102 0.70 CES1 (0.54) CYP2A6PARP10PARP11ALDH1A1HPGD
Formaldehyde SCHEMBL28028777 0.70 HNF4A (0.48) CYP2A6HNF4APARP10PARP11ALDH1A1
SCHEMBL2806539 0.69 ALDH1A1 (0.48) CYP2A6HNF4AALDH1A1HSD17B10HPGD
Water SCHEMBL432858 0.69 ALDH1A1 (0.48) CYP2A6HNF4AALDH1A1HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL21647364 0.69 ALDH1A1 (0.48) CYP2A6HNF4AALDH1A1HSD17B10HPGD
Phosphine SCHEMBL10935474 0.69 ALDH1A1 (0.48) CYP2A6HNF4AALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460547-A Separating actinide ions from aqueous, basic, carbonate containing solutions using mixed tertiary and quaternary amino anion exchange resins KERNFORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) 1984-07-17 US disclosed