M-Xylene

M-Xylene

SCHEMBL11058726

CC(C)CC(=O)CC(C)C.Cc1cccc(C)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.56
PARP1 P09874 1/20 0.44
ATM Q13315 1/20 0.42
SLC25A5 P05141 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27269348 0.85 ACHE (0.63) ACHESLC25A5HPGDTDP1SMN1; SMN2
Toluene SCHEMBL27263597 0.85 ACHE (0.63) ACHESLC25A5HPGDTDP1SMN1; SMN2
SCHEMBL3127902 0.83 CTBP2 (0.51) ACHE
P-Xylene SCHEMBL11050370 0.82 ACHE (0.77) ACHEATMSLC25A5HPGDTDP1
Methyl Isobutyl Ketone SCHEMBL10487290 0.79 ACHE (0.56) ACHESLC25A5HPGDTDP1SMN1; SMN2
SCHEMBL12960171 0.79 PARP1 (0.53) PARP1ATMHPGDTDP1SMN1; SMN2
O-Xylene SCHEMBL10819029 0.78 ACHE (0.55) ACHESLC25A5HPGDTDP1SMN1; SMN2
Methyl Alcohol SCHEMBL9172327 0.78 CYP2A6 (0.57) ACHESLC25A5TDP1SMN1; SMN2LMNA
Toluene SCHEMBL9504618 0.77 ACHE (0.54) ACHESLC25A5HPGDTDP1SMN1; SMN2
Toluene SCHEMBL28077055 0.77 ACHE (0.54) ACHESLC25A5HPGDTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4485197-A CONTAINING TRIORGANOTIN UNSATURATED CARBOXYLATE AND HYDROXY UNSATURATED ESTER NIPPON PAINT CO., LTD. (JP) 1984-11-27 US disclosed