Toluene

Toluene

SCHEMBL28077055

CC(C)CC(=O)CC(C)C.CC(C)CC(=O)CC(C)C.CCC(C)=O.Cc1ccccc1.c1ccccc1.c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.54
TDP1 Q9NUW8 3/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLC25A5 P05141 1/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 3/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 2/20 0.38
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HSD11B1 P28845 1/20 0.36
MTNR1A P48039 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9504618 1.00 ACHE (0.54) ACHETDP1KDM4EMAPTSMN1; SMN2
Methyl Isobutyl Ketone SCHEMBL10487290 0.91 ACHE (0.56) ACHETDP1KDM4EMAPTSMN1; SMN2
Methyl Isobutyl Ketone SCHEMBL8727203 0.91 ALDH1A1 (0.52) ACHETDP1KDM4EMAPTSMN1; SMN2
Toluene SCHEMBL27269348 0.91 ACHE (0.63) ACHETDP1KDM4EMAPTSMN1; SMN2
Toluene SCHEMBL27263597 0.91 ACHE (0.63) ACHETDP1KDM4EMAPTSMN1; SMN2
P-Xylene SCHEMBL28115019 0.89 TDP1 (0.50) ACHETDP1KDM4EMAPTSMN1; SMN2
O-Xylene SCHEMBL9644431 0.86 ALDH1A1 (0.47) ACHETDP1KDM4EMAPTSMN1; SMN2
Methyl Isobutyl Ketone SCHEMBL163328 0.85 ALDH1A1 (0.58) ACHETDP1KDM4EMAPTSMN1; SMN2
Toluene SCHEMBL9715675 0.85 LMNA (0.46) ACHETDP1MAPTSMN1; SMN2ALDH1A1
Toluene SCHEMBL11241972 0.84 LMNA (0.55) ACHETDP1MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed