Methyl Isobutyl Ketone

Methyl Isobutyl Ketone

SCHEMBL10487290

CC(=O)CC(C)C.CC(C)CC(=O)CC(C)C.Cc1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.56
ALDH1A1 P00352 6/20 0.52
TDP1 Q9NUW8 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
SLC25A5 P05141 1/20 0.42
LMNA P02545 3/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
HPGD P15428 3/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
STAT3 P40763 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Isobutyl Ketone SCHEMBL163328 0.94 ALDH1A1 (0.58) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Toluene SCHEMBL27269348 0.92 ACHE (0.63) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Toluene SCHEMBL27263597 0.92 ACHE (0.63) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Toluene SCHEMBL28077055 0.91 ACHE (0.54) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Toluene SCHEMBL9504618 0.91 ACHE (0.54) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Methyl Isobutyl Ketone SCHEMBL9328768 0.91 ALDH1A1 (0.54) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Methyl Isobutyl Ketone SCHEMBL11007468 0.89 ALDH1A1 (0.52) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Methyl Isobutyl Ketone SCHEMBL8727203 0.89 ALDH1A1 (0.52) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
P-Xylene SCHEMBL28115019 0.87 TDP1 (0.50) ACHEALDH1A1TDP1SMN1; SMN2KDM4E
Methyl Isobutyl Ketone SCHEMBL11127111 0.86 ALDH1A1 (0.48) ACHEALDH1A1TDP1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4877253-A Reusable bingo card MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-31 US disclosed