Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465332 | 0.79 | EPHX2 (0.38) | EPHX2EPHX1QDPRCYP1A2TDP1 | |
| SCHEMBL27827223 | 0.77 | EPHX2 (0.41) | EPHX2EPHX1MAPTQDPRCYP1A2 | |
| SCHEMBL27763152 | 0.75 | EPHX2 (0.40) | EPHX2EPHX1QDPRCYP1A2TDP1 | |
| SCHEMBL3457860 | 0.75 | EPHX2 (0.40) | EPHX2EPHX1MAPTQDPRCYP1A2 | |
| SCHEMBL23136277 | 0.74 | BRD4 (0.44) | EPHX2EPHX1MAPTCYP1A2TDP1 | |
| SCHEMBL18707162 | 0.72 | SMN1; SMN2 (0.41) | EPHX2EPHX1MAPTREV1 | |
| SCHEMBL13684331 | 0.71 | EPHX1 (0.38) | EPHX2EPHX1MAPT | |
| SCHEMBL11310192 | 0.71 | ALDH1A1 (0.47) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL57712 | 0.70 | CYP1A2 (0.44) | EPHX2EPHX1QDPRCYP1A2TDP1 | |
| SCHEMBL2998445 | 0.70 | CYP1A2 (0.44) | EPHX2EPHX1QDPRCYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486444-A | CARBONIC ANHYDRASE INHIBITORS | MERCK & CO., INC. (US) | 1984-12-04 | — | — | US | disclosed |