Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904580 | 0.70 | DRD2 (0.37) | DRD2DRD3DRD4 | |
| SCHEMBL6910114 | 0.61 | DRD2 (0.42) | DRD2DRD3DRD4 | |
| SCHEMBL8688541 | 0.60 | DRD2 (0.56) | DRD2DRD3DRD4 | |
| SCHEMBL9496955 | 0.60 | DRD2 (0.58) | DRD2DRD3DRD4 | |
| SCHEMBL6138233 | 0.58 | — | — | |
| SCHEMBL6911971 | 0.58 | DRD3 (0.42) | DRD2DRD3DRD4 | |
| SCHEMBL6908624 | 0.57 | — | — | |
| SCHEMBL8416141 | 0.57 | — | — | |
| SCHEMBL8689197 | 0.56 | DRD2 (0.79) | DRD2DRD3DRD4 | |
| SCHEMBL6903938 | 0.56 | DRD2 (0.39) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454150-A | 6,7,8,9-Tetrahydro-3H-benz(e)indol-7-amines and a method of dopamine receptor stimulation therewith | AYERST, MCKENNA & HARRISON INC. (US) | 1984-06-12 | — | — | US | disclosed |