Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683641 | 0.88 | ACE (0.73) | ACEHSD17B10FFAR2POLBGAA | |
| SCHEMBL10946334 | 0.87 | ACE (0.49) | ACEHSD17B10KIF11FFAR2MME | |
| SCHEMBL683637 | 0.85 | ACE (0.67) | ACEHSD17B10FFAR2POLBGAA | |
| SCHEMBL11062771 | 0.85 | ACE (0.67) | ACEHSD17B10FFAR2POLBGAA | |
| SCHEMBL11062272 | 0.85 | ACE (0.66) | ACEHSD17B10FFAR2POLBGAA | |
| SCHEMBL11385313 | 0.81 | ACE (0.43) | ACEHSD17B10KIF11FFAR2MME | |
| SCHEMBL11071092 | 0.81 | ACE (0.44) | ACEHSD17B10 | |
| SCHEMBL11385315 | 0.81 | ACE (0.43) | ACEHSD17B10KIF11FFAR2MME | |
| SCHEMBL11385050 | 0.80 | ACE (0.61) | ACEHSD17B10FFAR2POLBGAA | |
| SCHEMBL11190530 | 0.80 | ACE (0.62) | ACEHSD17B10FFAR2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |