Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100929 | 0.89 | HSD17B10 (0.52) | ACEHSD17B10 | |
| SCHEMBL11189829 | 0.84 | KDM4E (0.45) | ACEHSD17B10 | |
| SCHEMBL11247271 | 0.84 | KDM4E (0.45) | ACEHSD17B10 | |
| SCHEMBL11200469 | 0.83 | POLB (0.48) | ACE | |
| SCHEMBL11244020 | 0.83 | POLB (0.48) | ACE | |
| SCHEMBL11107571 | 0.82 | POLB (0.49) | ACE | |
| SCHEMBL11109577 | 0.81 | GAA (0.47) | ACE | |
| SCHEMBL11059109 | 0.81 | ACE (0.65) | ACEHSD17B10 | |
| SCHEMBL11104350 | 0.80 | POLB (0.46) | ACE | |
| SCHEMBL683556 | 0.80 | ACE (0.67) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |