Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054339 | 0.84 | LMNA (0.47) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL31173665 | 0.83 | KMT2A (0.53) | KMT2AALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL18700984 | 0.83 | KMT2A (0.53) | KMT2AALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL11031950 | 0.83 | TSHR (0.41) | KMT2AALDH1A1RAB9AGAAMAPT | |
| SCHEMBL29035604 | 0.82 | HCRTR1 (0.47) | KMT2ARAB9AGAAMEN1LMNA | |
| SCHEMBL3330772 | 0.81 | TSHR (0.58) | KMT2AALDH1A1L3MBTL1ATMHTT | |
| SCHEMBL8262732 | 0.81 | NR4A2 (0.47) | KMT2AALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL11063021 | 0.81 | ALDH1A1 (0.43) | KMT2AALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL16957106 | 0.80 | L3MBTL1 (0.45) | KMT2AALDH1A1RAB9AGAAMEN1 | |
| SCHEMBL5055100 | 0.79 | KMT2A (0.44) | KMT2AALDH1A1RAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | claimed |
| EP-0049498-A1 | Aluminium compounds that contain an organic rest, anti-sudorific agent containing these compounds as active components and application of this agent as an anti-sudorific agent | Richardson-Vicks, Inc. (US) | 1982-04-14 | — | — | EP | claimed |
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0049498-A1 | Aluminium compounds that contain an organic rest, anti-sudorific agent containing these compounds as active components and application of this agent as an anti-sudorific agent | Richardson-Vicks, Inc. (US) | 1982-04-14 | — | — | EP | disclosed |