Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338775 | 1.00 | MAOA (0.54) | MAOAMAOBKCNH2RIOK2KDM4E | |
| SCHEMBL20658872 | 0.77 | MAOA (0.56) | MAOAMAOBKCNH2RIOK2KDM4E | |
| SCHEMBL20658871 | 0.77 | MAOA (0.56) | MAOAMAOBKCNH2RIOK2KDM4E | |
| SCHEMBL20865430 | 0.74 | MAOA (0.71) | MAOAMAOBKCNH2KDM4EALDH1A1 | |
| SCHEMBL3499053 | 0.71 | MAOA (0.50) | MAOAMAOBKCNH2ALDH1A1 | |
| SCHEMBL3499052 | 0.71 | MAOA (0.50) | MAOAMAOBKCNH2ALDH1A1 | |
| SCHEMBL11883699 | 0.71 | NPC1 (0.49) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11883704 | 0.71 | NPC1 (0.49) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL407010 | 0.70 | MAOA (1.00) | MAOAMAOBKCNH2RIOK2ALDH1A1 | |
| SCHEMBL407009 | 0.70 | MAOA (1.00) | MAOAMAOBKCNH2RIOK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448880-A | Detection of β-lactamase utilizing a chromophoric cephalosporin composition | HOECHST AG. (DE) | 1984-05-15 | — | — | US | disclosed |
| EP-0018001-B1 | CHROMOPHORIC CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR UTILISATION, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-25 | — | — | EP | disclosed |
| US-4353824-A | DETECTORS OF BETA-LACTAMASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0018001-A2 | Chromophoric cephalosporin derivatives, process for their preparation and their utilisation, compositions containing them and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-29 | — | — | EP | disclosed |