SCHEMBL3499052

SCHEMBL3499052

CCN(C)/N=N\c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
KCNH2 Q12809 8/20 0.43
NOS3 P29474 2/20 0.41
NOS1 P29475 2/20 0.41
NOS2 P35228 2/20 0.41
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
PLAU P00749 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
ABCB1 P08183 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3499053 1.00 MAOA (0.50) MAOAMAOBKCNH2NOS3NOS1
SCHEMBL20658872 0.81 MAOA (0.56) MAOAMAOBKCNH2ADRA2AADRA2B
SCHEMBL20658871 0.81 MAOA (0.56) MAOAMAOBKCNH2ADRA2AADRA2B
SCHEMBL2470956 0.73 MAOA (0.77) MAOAMAOBKCNH2ADRA2AADRA2B
SCHEMBL275526 0.73 MAOA (0.77) MAOAMAOBKCNH2ADRA2AADRA2B
SCHEMBL29785641 0.73 MAOA (0.77) MAOAMAOBKCNH2ADRA2AADRA2B
SCHEMBL1850336 0.72 MAOA (0.46) MAOAMAOBKCNH2NOS3NOS1
SCHEMBL11059385 0.71 MAOA (0.54) MAOAMAOBKCNH2ALDH1A1
SCHEMBL338775 0.71 MAOA (0.54) MAOAMAOBKCNH2ALDH1A1
Benzene SCHEMBL10803509 0.71 MAOA (0.82) MAOAMAOBKCNH2ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed