SCHEMBL338775

SCHEMBL338775

Cc1ccc(N(C)N=Nc2ccccn2)cc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
KCNH2 Q12809 14/20 0.47
RIOK2 Q9BVS4 1/20 0.41
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11059385 1.00 MAOA (0.54) MAOAMAOBKCNH2RIOK2KDM4E
SCHEMBL20658872 0.77 MAOA (0.56) MAOAMAOBKCNH2RIOK2KDM4E
SCHEMBL20658871 0.77 MAOA (0.56) MAOAMAOBKCNH2RIOK2KDM4E
SCHEMBL20865430 0.74 MAOA (0.71) MAOAMAOBKCNH2KDM4EALDH1A1
SCHEMBL3499053 0.71 MAOA (0.50) MAOAMAOBKCNH2ALDH1A1
SCHEMBL3499052 0.71 MAOA (0.50) MAOAMAOBKCNH2ALDH1A1
SCHEMBL11883699 0.71 NPC1 (0.49) KDM4EALDH1A1HSD17B10
SCHEMBL11883704 0.71 NPC1 (0.49) KDM4EALDH1A1HSD17B10
SCHEMBL407010 0.70 MAOA (1.00) MAOAMAOBKCNH2RIOK2ALDH1A1
SCHEMBL407009 0.70 MAOA (1.00) MAOAMAOBKCNH2RIOK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108144072-A For diagnosing the radiopharmaceutical of agglutinin receptor height expression tumour 北京大学 2018-06-12 CN claimed
US-9902989-B2 Methods for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2018-02-27 US claimed
US-20160138076-A1 Methods And Compositions For The Detection Of Beta-Lactamases BECTON, DICKINSON AND COMPANY (US) 2016-05-19 US claimed
US-9085794-B2 Kits for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2015-07-21 US claimed
US-8778303-B2 99mTc-labeled 19 amino acid containing peptide for use as phosphatidylethanolamine binding molecular probe and radiopharmaceutical THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2014-07-15 US claimed
US-20140080164-A1 METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES BECTON, DICKINSON AND COMPANY (US) 2014-03-20 US claimed
US-20130058865-A1 99mTc-LABELED 19 AMINO ACID CONTAINING PEPTIDE FOR USE AS PHOSPHATIDYLETHANOLAMINE BINDING MOLECULAR PROBE AND RADIOPHARMACEUTICAL MEDICAL COLLEGE OF WISCONSIN, INC. 2013-03-07 US claimed
US-8389234-B2 Kits for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2013-03-05 US claimed
US-8097434-B2 Methods for the detection of beta-lactamases BECTON, DICKINSON AND COMPANY (US) 2012-01-17 US claimed
CN-119746820-B Preparation method and application of loofah sponge adsorbent for efficiently recycling gold (III) in electronic waste 昆明理工大学 2025-10-03 CN disclosed
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY BeijingGiluntidePharmaceuticalCo.,Ltd. (CN) 2025-09-25 US disclosed
US-12357712-B2 Targeted radiopharmaceutical for tumor and its use in the imaging-guided combination therapy of targeted radiotherapy and immunotherapy BEIJING GILUNTIDE PHARMACEUTICAL CO., LTD. (CN) 2025-07-15 US disclosed
US-12345641-B2 Fluorescence quenching immunoassay IDEZZ Laboratories, Inc. (US) 2025-07-01 US disclosed
CN-119746820-A Preparation method and application of loofah sponge adsorbent for efficiently recycling gold (III) in electronic waste 昆明理工大学 2025-04-04 CN disclosed
WO-1993003346-A1 TEST FOR THE RAPID EVALUATION OF ISCHEMIC STATES AND KIT DIAGNOSTIC MARKERS, INC. (US) 1993-02-18 WO disclosed
EP-0312543-A4 _I(IN SITU) ACTIVE COMPOUND ASSEMBLY 1990-12-27 EP disclosed
EP-0312543-A1 $i(IN SITU) ACTIVE COMPOUND ASSEMBLY SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-04-26 EP disclosed
US-4812449-A SYNTHESIS AT TARGET SITES, MICROENVIRONMENT SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-03-14 US disclosed
US-4764462-A IMMOBILIZED ON SOLID SUPPORT GEORGETOWN UNIVERSITY (US) 1988-08-16 US disclosed
WO-1988000047-A1 IN SITU ACTIVE COMPOUND ASSEMBLY SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1988-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130058865-A1 99mTc-LABELED 19 AMINO ACID CONTAINING PEPTIDE FOR USE AS PHOSPHATIDYLETHANOLAMINE BINDING MOLECULAR PROBE AND RADIOPHARMACEUTICAL PHOSPHO1, PEBP1, PTDSS1 MAOA 4711/4885MAOB 4232/4885KCNH2 3936/4885
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY CD274, ITGB1, ITGA1 MAOA 4825/4885MAOB 4720/4885KCNH2 3488/4885
US-12345641-B2 Fluorescence quenching immunoassay NQO2, FCGRT, MPO MAOA 438/4885MAOB 363/4885KCNH2 3624/4885
US-12357712-B2 Targeted radiopharmaceutical for tumor and its use in the imaging-guided combination therapy of targeted radiotherapy and immunotherapy CD274, ITGB1, ITGA1 MAOA 4825/4885MAOB 4720/4885KCNH2 3488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.