Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587355 | 0.76 | MAOB (0.52) | PYCR1IDO1MIFLMNACYP2A6 | |
| SCHEMBL28021056 | 0.73 | IDO1 (0.46) | IDO1TAAR1AGXTSLC6A4LMNA | |
| SCHEMBL6140808 | 0.72 | PYCR1 (0.46) | PYCR1IDO1MIFTAAR1ALDH1A1 | |
| SCHEMBL9782934 | 0.72 | TSHR (0.42) | LMNA | |
| SCHEMBL5506050 | 0.70 | IDO1 (0.48) | IDO1TAAR1AGXTSLC6A4LMNA | |
| SCHEMBL453913 | 0.70 | IDO1 (0.48) | IDO1TAAR1AGXTSLC6A4LMNA | |
| SCHEMBL11689835 | 0.70 | LOXL2 (0.50) | PYCR1IDO1ALDH1A1ATMMEN1 | |
| SCHEMBL23358983 | 0.69 | IDO1 (0.46) | IDO1TAAR1AGXTSLC6A4LMNA | |
| SCHEMBL1427989 | 0.69 | ALDH1A1 (0.52) | IDO1TAAR1AGXTSLC6A4LMNA | |
| SCHEMBL2123502 | 0.69 | IDO1 (0.46) | IDO1TAAR1AGXTSLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486444-A | CARBONIC ANHYDRASE INHIBITORS | MERCK & CO., INC. (US) | 1984-12-04 | — | — | US | disclosed |