Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210578 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 | |
| SCHEMBL4213117 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HSD17B10NPSR1POLB | |
| SCHEMBL2999986 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 | |
| SCHEMBL888446 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 | |
| SCHEMBL723852 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 | |
| SCHEMBL3010190 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HSD17B10NPSR1POLBEPHX2 | |
| SCHEMBL888279 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HSD17B10NPSR1POLBEPHX2 | |
| SCHEMBL4211760 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HSD17B10NPSR1POLBEPHX2 | |
| SCHEMBL451991 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 | |
| SCHEMBL9180883 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TP53CYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442015-A | LIQUID, HYDROLYZABLE ORGANOSILANE | Packo, Joseph J. (US) | 1984-04-10 | — | — | US | disclosed |