SCHEMBL888279

SCHEMBL888279

CO[Si](NC1CCCC1)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.32
EPHX2 P34913 2/20 0.31
TSHR P16473 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888446 0.97 ALDH1A1 (0.39) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL4211760 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL3010190 0.79 ALDH1A1 (0.35) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL4213117 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10NPSR1POLB
SCHEMBL723852 0.77 ALDH1A1 (0.39) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL2999986 0.77 ALDH1A1 (0.39) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL11059965 0.75 ALDH1A1 (0.38) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL4210578 0.75 ALDH1A1 (0.38) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL888397 0.73 NPSR1 (0.34) ALDH1A1HSD17B10NPSR1
SCHEMBL4206954 0.72 NPSR1 (0.37) ALDH1A1HSD17B10NPSR1POLBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
US-8546290-B2 Solid catalyst component for olefin polymerization, manufacturing method, and catalyst and olefin polymer manufacturing method TOHO TITANIUM CO., LTD. (JP) 2013-10-01 US disclosed
US-20110269926-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD TOHO TITANIUM CO., LTD. (JP) 2011-11-03 US disclosed
EP-2374821-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, MANUFACTURING METHOD, AND CATALYST AND OLEFIN POLYMER MANUFACTURING METHOD Toho Titanium CO., LTD. (JP) 2011-10-12 EP disclosed