⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468894 | 1.00 | — | — | |
| SCHEMBL10584685 | 0.87 | — | — | |
| SCHEMBL3089481 | 0.83 | CHRM1 (0.36) | — | |
| SCHEMBL15513449 | 0.81 | ALOX15 (0.36) | — | |
| SCHEMBL108250 | 0.81 | — | — | |
| SCHEMBL8853474 | 0.81 | — | — | |
| SCHEMBL2721856 | 0.81 | — | — | |
| SCHEMBL7568882 | 0.80 | — | — | |
| SCHEMBL11118295 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL373895 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580886-B2 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING CORPORATION (US) | 2013-11-12 | — | — | US | claimed |
| EP-2424740-B1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING (US) | 2013-10-16 | — | — | EP | claimed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | claimed |
| US-20120059121-A1 | Elastomer Compositions Modified By Silanes | DOW CORNING EUROPE SA (BE) | 2012-03-08 | — | — | US | claimed |
| EP-2424740-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | Dow Corning Corporation (US) | 2012-03-07 | — | — | EP | claimed |
| WO-2010125123-A1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING CORPORATION (US) | 2010-11-04 | — | — | WO | claimed |
| US-9518072-B2 | Ester-functional silanes and the preparation and use thereof; and use of iminium compounds as phase transfer catalysts | DOW CORNING CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2762482-B1 | PROCESS FOR PURIFYING AN ACRYLOYLOXYSILANE | DOW CORNING (US) | 2016-10-26 | — | — | EP | disclosed |
| EP-2788436-B1 | TREATMENT OF FILLER WITH SILANE | DOW CORNING (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9249164-B2 | Process for preparing an acryloyloxysilane | DOW SILICONES CORPORATION | 2016-02-02 | — | — | US | disclosed |
| US-9080057-B2 | Treatment of filler with silane | DOW CORNING CORPORATION (US) | 2015-07-14 | — | — | US | disclosed |
| US-20140350152-A1 | Treatment Of Filler With Silane | DOW SILICONES CORPORATION | 2014-11-27 | — | — | US | disclosed |
| US-20140329976-A1 | Treatment Of Filler With Silane | DOW CORNING EUROPE S.A. (BE) | 2014-11-06 | — | — | US | disclosed |
| US-8580886-B2 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2621936-A2 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | Dow Corning Corporation (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130184482-A1 | Process For Preparing An Acryloyloxysilane | DOW CORNING CORPORATION (US) | 2013-07-18 | — | — | US | disclosed |
| WO-2013083748-A1 | TREATMENT OF FILLER WITH SILANE | DOW CORNING CORPORATION (US) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013083746-A1 | TREATMENT OF FILLER WITH SILANE | DOW CORNING CORPORATION (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2012050761-A2 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW CORNING CORPORATION (US) | 2012-04-19 | — | — | WO | disclosed |