SCHEMBL11060073

SCHEMBL11060073

C=CCSc1ccnc(Cl)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HPGD P15428 4/20 0.34
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
CRHBP P24387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10848424 0.75 KDM4E (0.39) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL5139546 0.73 L3MBTL1 (0.50) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL11481094 0.73 KMT2A (0.38) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL6821120 0.73 KMT2A (0.45) KMT2AHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL1984295 0.72
SCHEMBL6319391 0.72 GRM5 (0.40) L3MBTL1
SCHEMBL5738824 0.71 GAA (0.56) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL4322396 0.71 ALDH1A1 (0.34) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL11193955 0.70 PKM (0.42) GAAL3MBTL1MEN1KMT2AHPGD
SCHEMBL20165928 0.70 HSD17B10 (0.50) GAAMEN1KMT2AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0080917-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIO-PYRIMIDINE DERIVATIVES AND PYRIDATE, AND PROCESS FOR THE TREATMENT OF CORPS WITH THE AID OF SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1985-01-23 EP claimed
EP-0070219-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIOPYRIMIDINE DERIVATIVES AND 2,6-DINITROANILINE DERIVATIVES, AND METHOD OF TREATING CROPS WITH SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1984-10-24 EP claimed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP claimed
WO-1983000275-A1 HERBICIDAL COMPOSITIONS BOUTEMY, Gérard 1983-02-03 WO claimed
EP-0070219-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and 2,6-dinitroaniline derivatives, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP claimed
EP-0070238-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and Metribuzin, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP claimed
EP-0080917-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIO-PYRIMIDINE DERIVATIVES AND PYRIDATE, AND PROCESS FOR THE TREATMENT OF CORPS WITH THE AID OF SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1985-01-23 EP disclosed
EP-0080917-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIO-PYRIMIDINE DERIVATIVES AND PYRIDATE, AND PROCESS FOR THE TREATMENT OF CORPS WITH THE AID OF SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1985-01-23 EP disclosed
EP-0070219-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIOPYRIMIDINE DERIVATIVES AND 2,6-DINITROANILINE DERIVATIVES, AND METHOD OF TREATING CROPS WITH SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1984-10-24 EP disclosed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP disclosed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP disclosed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP disclosed
WO-1983000275-A1 HERBICIDAL COMPOSITIONS BOUTEMY, Gérard 1983-02-03 WO disclosed
EP-0070238-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and Metribuzin, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed
EP-0070219-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and 2,6-dinitroaniline derivatives, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed
EP-0070219-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and 2,6-dinitroaniline derivatives, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed
EP-0070219-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and 2,6-dinitroaniline derivatives, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed
EP-0070238-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and Metribuzin, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed
EP-0070238-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthiopyrimidine derivatives and Metribuzin, and method of treating crops with said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-01-19 EP disclosed