Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783931 | 1.00 | MAPT (0.65) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL14745637 | 0.81 | MAPT (0.68) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL14745638 | 0.81 | MAPT (0.68) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| Maleic Acid SCHEMBL28501255 | 0.79 | NR4A1 (0.59) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2911444 | 0.79 | TLR9 (0.87) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2911445 | 0.79 | TLR9 (0.87) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL482915 | 0.79 | MAPT (1.00) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL482916 | 0.79 | MAPT (1.00) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL6263294 | 0.78 | MAPT (0.57) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL3046452 | 0.78 | MAPT (0.61) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486429-A | ANTICIDS | ROUSSEL UCLAF (FR) | 1984-12-04 | — | — | US | claimed |
| US-4486429-A | ANTICIDS | ROUSSEL UCLAF (FR) | 1984-12-04 | — | — | US | disclosed |