Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7649134 | 0.85 | HPGD (0.64) | RAB9ANPC1HPGDKMT2AMAPT | |
| Oxalic Acid SCHEMBL11574387 | 0.83 | HPGD (0.61) | RAB9ANPC1HPGDKMT2AMAPT | |
| Bicarbonate SCHEMBL28328867 | 0.83 | HPGD (0.61) | RAB9ANPC1HPGDKMT2AMAPT | |
| Acetone SCHEMBL28096825 | 0.83 | RAB9A (0.61) | RAB9ANPC1HPGDKMT2AMAPT | |
| Acetic Acid SCHEMBL2680615 | 0.83 | RAB9A (0.61) | RAB9ANPC1HPGDKMT2AMAPT | |
| Formic Acid SCHEMBL1042545 | 0.81 | RAB9A (0.54) | RAB9ANPC1HPGDKMT2AMAPT | |
| Fumaric Acid SCHEMBL21145268 | 0.81 | HCAR2 (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| Fumaric Acid SCHEMBL21145270 | 0.81 | HCAR2 (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| Maleic Acid SCHEMBL29875749 | 0.81 | HCAR2 (0.50) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL4022487 | 0.81 | LMNA (0.49) | NR4A1RAB9ANPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989079-B | Dental composition | 登特斯普伊德特雷有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115714235-A | Separator and battery including the same | 武汉微美新材料科技有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115347324-A | Ceramic coating, and diaphragm and lithium ion battery comprising same | 武汉微美新材料科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-111989079-A | Dental composition | 登特斯普伊德特雷有限公司 | 2020-11-24 | — | — | CN | disclosed |