Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.58 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.58 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.58 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.58 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GABRP | O00591 | 4/20 | 0.54 |
| ▸ | GABRD | O14764 | 4/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045004 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497658 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL497657 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL13988189 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11345742 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL6044996 | 1.00 | MEN1 (0.58) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL11696291 | 0.90 | MEN1 (0.57) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| Acetic Acid SCHEMBL29519885 | 0.89 | GABRP (0.66) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL23872369 | 0.89 | GABRA1 (0.69) | MEN1KMT2AAKR1B10AKR1B1LMNA | |
| SCHEMBL598324 | 0.89 | GABRA1 (0.69) | MEN1KMT2AAKR1B10AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460509-A | STEROIDS WITH HETERO RING SIDE CHAIN | BETH ISRAEL MEDICAL CENTER (US) | 1984-07-17 | — | — | US | disclosed |