SCHEMBL11060758

SCHEMBL11060758

CCCCN(CCCC)c1cc(S(=O)(=O)Nc2ccccc2)ccc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.51
LIMK2 P53671 1/20 0.51
PKM P14618 4/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
WDR5 P61964 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 1/20 0.47
ADRB2 P07550 2/20 0.45
ADRB1 P08588 2/20 0.45
ADRB3 P13945 2/20 0.45
GHSR Q92847 1/20 0.45
HTT P42858 3/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11057043 0.87 ALDH1A1 (0.54) LIMK1LIMK2PKMCA12CA9
SCHEMBL11060761 0.78 CA12 (0.44) LIMK1LIMK2CA12CA9CA1
SCHEMBL30760637 0.75 TDP1 (0.52) LIMK1LIMK2PKMCA12CA9
SCHEMBL670586 0.71 CA12 (0.53) PKMCA12CA9CA1CA2
SCHEMBL31689632 0.71 CA12 (0.60) PKMCA12CA9CA1CA2
SCHEMBL27756562 0.71 CA12 (0.60) PKMCA12CA9CA1CA2
SCHEMBL11070041 0.71 KMT2A (0.60) PKMCA12CA9CA1CA2
SCHEMBL8335154 0.69 ADRB2 (0.57) LIMK1LIMK2PKMCA12CA9
SCHEMBL11062540 0.69 ALDH1A1 (0.49) LIMK1LIMK2CA12CA9WDR5
Water SCHEMBL27650777 0.69 FFAR1 (0.72) LIMK1LIMK2PKMCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479899-A OF POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed
US-4452609-A Dyeing red with 2,6-dicyano-2'-sulfonamido-4'-amino-azo-benzenes BAYER AKTIENGESELLSCHAFT (DE) 1984-06-05 US disclosed