SCHEMBL11060901

SCHEMBL11060901

Cc1cccc2c(N)c3ccccc3nc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.66
ALDH1A1 P00352 6/20 0.63
HPGD P15428 5/20 0.63
KDM4E B2RXH2 5/20 0.63
HSD17B10 Q99714 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
ACHE P22303 4/20 0.63
GLA P06280 2/20 0.63
CASP1 P29466 2/20 0.63
CASP7 P55210 2/20 0.63
CHRM2 P08172 2/20 0.63
ADRA2A P08913 2/20 0.63
ADORA3 P0DMS8 2/20 0.63
CHRM1 P11229 2/20 0.63
SLC6A2 P23975 2/20 0.63
OPRM1 P35372 2/20 0.63
KCNH2 Q12809 2/20 0.63
NQO2 P16083 1/20 0.63
MAOA P21397 1/20 0.63
DRD1 P21728 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30182735 1.00 CYP1A2 (0.66) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11060868 0.86 KDM4E (0.61) CYP1A2ALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL27977387 0.82 KDM1A (0.50) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11057014 0.82 CYP1A2 (0.68) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11051332 0.82 ALDH1A1 (0.55) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL6791707 0.79 MAOA (0.61) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL17060429 0.79 CYP1A2 (0.50) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL12886828 0.79 KDM1A (0.48) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11052646 0.79 ALDH1A1 (0.61) CYP1A2ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL11051320 0.79 CYP1A2 (0.64) CYP1A2ALDH1A1HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160131658-A1 METHOD AND KIT FOR ASSESSING VIABLE CELLS CHEMOMETEC AS (DK) 2016-05-12 US disclosed
US-4462993-A REACTION WITH A SUGAR IN PRESENCE OF ACID CATALYST BIOGAL GYOGYSZERGYAR (HU) 1984-07-31 US disclosed