Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977387 | 0.81 | KDM1A (0.50) | MAOAKDM1AMEN1KMT2ANPC1 | |
| SCHEMBL11060901 | 0.79 | CYP1A2 (0.66) | MAOAKDM1AMEN1KMT2ANPC1 | |
| SCHEMBL30182735 | 0.79 | CYP1A2 (0.66) | MAOAKDM1AMEN1KMT2ANPC1 | |
| SCHEMBL28054584 | 0.78 | MAOA (0.61) | MAOAMAOBCYP1A2PARP1GPR3 | |
| SCHEMBL17060429 | 0.78 | CYP1A2 (0.50) | KDM1AMEN1KMT2ANPC1HCRTR1 | |
| SCHEMBL12886828 | 0.78 | KDM1A (0.48) | MAOAKDM1AMEN1KMT2ANPC1 | |
| SCHEMBL1186255 | 0.78 | KDM1A (0.48) | MAOAKDM1AMEN1KMT2ANPC1 | |
| SCHEMBL15131691 | 0.78 | MAOA (0.73) | MAOAMAOBMEN1KMT2ANPC1 | |
| SCHEMBL7122711 | 0.77 | NQO2 (0.59) | MAOAMAOBKDM1AMEN1KMT2A | |
| SCHEMBL27889436 | 0.77 | MAOA (1.00) | MAOAMAOBKDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057004-B | N-o-substituted phenyl benzamide-4-methylaminoacridine compound and preparation method and application thereof | 宁波大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-111057004-A | N-ortho-substituted phenyl benzamide-4-methylaminoacridine compound and preparation method and application thereof | 宁波大学 | 2020-04-24 | — | — | CN | disclosed |
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
| US-6821983-B2 | INHIBITORS OF TOPOISOMERASE II CAN EXHIBIT ANTITUMOR ACTIVITY | ACADEMIA SINICA (TW) | 2004-11-23 | — | — | US | disclosed |
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | ACADEMIA SINICA (TW) | 2004-10-07 | — | — | US | disclosed |
| US-4795826-A | CHEMICAL INTERMEDIATES FOR BACTERICIDES AND ANTITUMOR AGENTS | ATWELL GRAHAM J (NZ) | 1989-01-03 | — | — | US | disclosed |
| EP-0095355-B1 | SUBSTITUTED O-PHENYLENEDIAMINE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |
| EP-0073155-B1 | COMPOUNDS HAVING ANTITUMOUR ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4603125-A | Substituted o-phenylenediamine acridine compounds having antitumor activity | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1986-07-29 | — | — | US | disclosed |
| US-4537729-A | ANTITUMOR AGENTS | DEVELOPMENT OF FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1985-08-27 | — | — | US | disclosed |
| US-4479000-A | ANTITUMOR AGENTS | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-10-23 | — | — | US | disclosed |
| EP-0095355-A1 | Substituted o-phenylenediamine compounds | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| EP-0073155-A2 | Compounds having antitumour activity | WARNER-LAMBERT COMPANY (US) | 1983-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | MAOA 4191/4885MAOB 4361/4885KDM1A 1168/4885 |
| US-20040198765-A1 | 5-(9-ACRIDINYLAMINO)-TOLUIDINE COMPOUNDS | DPP9, NANP, NAT1 | MAOA 820/4885MAOB 1338/4885KDM1A 3382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.