Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060025 | 0.80 | RXRA (0.41) | RXRARXRBPDCD1CD274PGR | |
| SCHEMBL845280 | 0.78 | PDCD1 (0.44) | PDCD1CD274GCGRPARP10PARP11 | |
| SCHEMBL8679020 | 0.77 | CD274 (0.47) | PDCD1CD274GCGRPARP10PARP11 | |
| SCHEMBL19018491 | 0.72 | PDCD1 (0.50) | PDCD1CD274PGRHTR7PSMB5 | |
| SCHEMBL27967839 | 0.71 | RXRA (0.46) | RXRARXRBPDCD1CD274PGR | |
| SCHEMBL9792869 | 0.70 | PDCD1 (0.54) | PDCD1CD274PARP10PARP11ESR2 | |
| SCHEMBL8679266 | 0.68 | CD274 (0.50) | PDCD1CD274PARP10PARP11ESR2 | |
| SCHEMBL16938170 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL22137224 | 0.67 | HDAC7 (0.45) | RXRARXRBPGRESR2PSMB5 | |
| SCHEMBL21173403 | 0.67 | PGR (0.44) | RXRARXRBPGRESR2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473709-A | Pyrethroid intermediates and process | FMC CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |