Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 4/20 | 0.69 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.69 |
| ▸ | SCN1A | P35498 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066967 | 0.89 | SCN1A (0.55) | SCN5ASCN9ASCN1AKCNH2ADRB2 | |
| SCHEMBL11073906 | 0.87 | SCN1A (0.70) | SCN5ASCN9ASCN1AADRB2ADRB1 | |
| SCHEMBL11072939 | 0.87 | DRD4 (0.62) | SCN5ASCN9ASCN1AADRB2ADRB1 | |
| SCHEMBL11073911 | 0.85 | SCN1A (0.60) | SCN5ASCN9ASCN1AKCNH2ADRB2 | |
| SCHEMBL10571929 | 0.84 | SCN5A (0.68) | SCN5ASCN9ASCN1AKCNH2ADRB2 | |
| SCHEMBL11071869 | 0.84 | SCN1A (0.55) | SCN5ASCN9ASCN1AKCNH2SLC18A3 | |
| Hydrochloric Acid SCHEMBL10572281 | 0.83 | SCN5A (0.67) | SCN5ASCN9ASCN1AKCNH2ADRB2 | |
| SCHEMBL11073435 | 0.82 | HTR7 (0.48) | SCN5ASCN9ASCN1ADRD2DRD4 | |
| SCHEMBL10573893 | 0.82 | SCN5A (0.56) | SCN5ASCN9ASCN1AKCNH2ADRB2 | |
| SCHEMBL11069036 | 0.81 | SCN1A (0.52) | SCN5ASCN9ASCN1AKCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57035588-A | — | — | None | — | — | JP | disclosed |
| JP-56043280-A | — | — | None | — | — | JP | disclosed |
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |
| JP-S5735588-A | CARBOSTYRILE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-02-26 | — | — | JP | disclosed |
| JP-S5643280-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1981-04-21 | — | — | JP | disclosed |