Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061316 | 0.89 | SCN5A (0.69) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11071304 | 0.87 | DRD4 (0.62) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL10572684 | 0.84 | SCN5A (0.54) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11073435 | 0.82 | HTR7 (0.48) | SCN1ASCN5ASCN9ADRD4TSHR | |
| Hydrochloric Acid SCHEMBL11070539 | 0.81 | HTR7 (0.47) | SCN1ASCN5ASCN9ADRD4SIGMAR1 | |
| SCHEMBL10666537 | 0.81 | SCN1A (0.51) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11071272 | 0.81 | DRD4 (0.45) | DRD4KCNH2TSHRL3MBTL1SLC18A3 | |
| SCHEMBL11066783 | 0.79 | SLC18A3 (0.38) | SCN1ASCN5ASCN9AKCNH2SLC18A3 | |
| SCHEMBL11066964 | 0.77 | SCN1A (0.41) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11070047 | 0.77 | DRD2 (0.51) | SCN1ASCN5ASCN9AHTR1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |