Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573810 | 0.85 | KCNH2 (0.61) | SCN1ASCN5ASCN9AKCNH2MEN1 | |
| SCHEMBL11064138 | 0.84 | KCNH2 (0.64) | SCN1ASCN5ASCN9AKCNH2SLC18A3 | |
| SCHEMBL11073822 | 0.84 | KCNH2 (0.54) | SCN1ASCN5ASCN9AKCNH2 | |
| SCHEMBL11061316 | 0.81 | SCN5A (0.69) | SCN1ASCN5ASCN9AKCNH2SLC18A3 | |
| SCHEMBL11071869 | 0.76 | SCN1A (0.55) | SCN1ASCN5ASCN9AKCNH2SLC18A3 | |
| SCHEMBL11066799 | 0.76 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL11068217 | 0.76 | KCNH2 (0.57) | SCN1ASCN5ASCN9AKCNH2 | |
| SCHEMBL11066876 | 0.76 | KCNH2 (0.51) | SCN1ASCN5ASCN9AKCNH2MEN1 | |
| SCHEMBL11073906 | 0.75 | SCN1A (0.70) | SCN1ASCN5ASCN9AHTR1A | |
| SCHEMBL11065488 | 0.75 | KCNH2 (0.43) | SCN1ASCN5ASCN9AKCNH2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |