Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835 | 0.85 | ALDH1A1 (0.60) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL2523863 | 0.82 | KDM4E (0.62) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL8940421 | 0.81 | GAA (0.65) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL5059395 | 0.80 | PTGS1 (0.55) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL27472857 | 0.79 | GAA (0.62) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL8651089 | 0.78 | KDM4E (0.68) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL8940124 | 0.78 | KDM4E (0.68) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL28880300 | 0.77 | TSHR (0.81) | GAAKDM4ETSHRPOLBALDH1A1 | |
| SCHEMBL537958 | 0.76 | KDM4E (0.69) | GAAKDM4ETSHRCYP1A2CYP2D6 | |
| Ramifenazone SCHEMBL24763 | 0.76 | KDM4E (1.00) | GAAKDM4ETSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455298-A | MOLLUSC EXTRACT | MCFARLANE STUART J (NZ) | 1984-06-19 | — | — | US | disclosed |
| EP-0010061-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING A MOLLUSC EXTRACT | Mc Farlane, Stuart John (NZ) | 1983-07-13 | — | — | EP | disclosed |
| WO-1980000661-A1 | PHARMACEUTICAL PREPARATIONS | CROFT J (NZ) | 1980-04-17 | — | — | WO | disclosed |
| EP-0010061-A1 | Pharmaceutical preparations containing a mollusc extract | Mc Farlane, Stuart John (NZ) | 1980-04-16 | — | — | EP | disclosed |
| EP-0007572-A1 | Pharmaceutical mixtures containing an amantadine compound | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | disclosed |