Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061329 | 0.85 | GAA (0.62) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL3280911 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL8940421 | 0.80 | GAA (0.65) | ALDH1A1KDM4EMAPTGAAKMT2A | |
| SCHEMBL27472857 | 0.78 | GAA (0.62) | ALDH1A1KDM4EMAPTGAAKMT2A | |
| SCHEMBL1476459 | 0.77 | KDM4E (0.52) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8940124 | 0.77 | KDM4E (0.68) | ALDH1A1KDM4EMAPTGAAKMT2A | |
| SCHEMBL537958 | 0.75 | KDM4E (0.69) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL2523863 | 0.75 | KDM4E (0.62) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL4447238 | 0.74 | KDM4E (0.68) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL8651089 | 0.74 | KDM4E (0.68) | ALDH1A1KDM4EMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401633-A | Pest control method, pest control agent composition, and pest control agent set | 日本曹达株式会社 | 2022-04-26 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-4168092-B1 | BALLOON CATHETER WITH PRECISION DRUG-ELUTING CAPABILITY | BARD INC C R (US) | 2026-05-27 | — | — | EP | disclosed |
| US-20260097102-A1 | Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors | REGENERON PHARMA (US) | 2026-04-09 | — | — | US | disclosed |
| US-12472241-B2 | Treatment of respiratory disorders with arachidonate 15-lipoxygenase (ALOX15) inhibitors | REGENERON PHARMACEUTICALS, INC. (US) | 2025-11-18 | — | — | US | disclosed |
| US-12458392-B2 | Scoring balloon with translating scoring wires | C.R. BARD, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| CN-222476374-U | Coking wastewater treatment equipment | 内蒙古伊泰同达煤炭有限责任公司 | 2025-02-14 | — | — | CN | disclosed |
| US-12167883-B2 | Medical device including expandable muscle polymer | BARD PERIPHERAL VASCULAR, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-4210606-B1 | MEDICAL DEVICE INCLUDING EXPANDABLE MUSCLE POLYMER | BARD PERIPHERAL VASCULAR INC (US) | 2024-05-01 | — | — | EP | disclosed |
| EP-3970643-B1 | SCORING BALLOON WITH TRANSLATING SCORING WIRES | BARD INC C R (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-1996032120-A1 | ANIONIC OXYGEN RADICALS CONTAINING THERAPEUTIC AGENTS AND THEIR USE IN PAIN RELIEF | GOLDSTEIN & LEWIN TECHNOLOGY GMBH (DE) | 1996-10-17 | — | — | WO | disclosed |
| US-5492937-A | ALKYL HYDROXYALKYL CELLULOSE AS WATER SOLUBLE NONIONIC CELLULOSE ETHER USED AS CARRIER WITH CATIONIC OR ANIONIC SURFACTANT | PHARMACIA AB (SE) | 1996-02-20 | — | — | US | disclosed |
| US-5446070-A | Flexible, finite, bioadhesive, therapeutical agent in solid form | NOVER PHARMACEUTICALS, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| WO-1995016465-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ALKYL POLYOXYALKYLENE CARBOXYLATES | SANDOZ LTD. (CH) | 1995-06-22 | — | — | WO | disclosed |
| EP-0558586-A1 | A GEL-FORMING LIQUID CARRIER COMPOSITION. | KABI PHARMACIA AB (SE) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009307-A1 | A GEL-FORMING LIQUID CARRIER COMPOSITION | KABI PHARMACIA AB (SE) | 1992-06-11 | — | — | WO | disclosed |
| US-4503145-A | DIAGNOSIS OF LIVER DISORDERS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-03-05 | — | — | US | disclosed |
| US-4478942-A | CATIONIC DYE BOUND TO ANIONIC POLYMER FOR ASSAY OF HYDROGEN PEROXIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| US-4418037-A | PYROGALLOL DERIVATIVE STORAGE STABILIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260097102-A1 | Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors | ALOX15, ALOX15B, ALOX5 | PTGS2 34/4885ALDH1A1 900/4885KDM4E 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.