Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924279 | 0.90 | ALDH1A1 (0.35) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL11168567 | 0.87 | CES2 (0.42) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL5165391 | 0.84 | AKR1B1 (0.39) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL21206465 | 0.82 | LMNA (0.34) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28923839 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL11859866 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL29260480 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL28384093 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL1043350 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR | |
| SCHEMBL11173653 | 0.80 | CES2 (0.45) | ALDH1A1KMT2AMEN1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483869-A | DETOXIFICATION OF THE LIVER, BURNS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1984-11-20 | — | — | US | disclosed |